Exosomes

What Are Exosomes?

Exosomes are tiny vesicles, also known as extracellular vesicles, popular as acellular, secreted by almost all human, animal and plant cells. Think of them as a powerhouse of regenerative messengers of your body—they carry important information from one cell to another. These messages can be in proteins, peptides, messenger RNA, micro RNA, nucleotides, enzymes, and more. While PRP is autologous, exosomes are commercially available and ready to use. For instance, if there’s inflammation in your body, a cell might release exosomes with a message saying, “Stop the inflammation.” Similarly, exosomes might send a message to speed up the healing process if there’s a wound. This ability to communicate and regulate bodily functions makes exosomes a powerful tool in aesthetic medicine.

Exosomes in Aesthetic Medicine(No Large randomized controlled study)

In this section, we’re focusing only on the possible role of topical application & regenerative benefits of exosomes in aesthetic medicine. Exosome science, as therapeutic and diagnostic research, has exploded in the last 15 years. While exosomes have a wide range of applications in fields like neurology, cardiovascular surgery, and oncology, the scope of this page is limited to their role in non-surgical aesthetic procedures. The exosomes may have some benefit in aesthetic medicine. 

Types of Exosomes

As we mentioned, exosomes are messengers released by cells. When they come from stem cells—such as those from bone marrow, placenta, umbilical cord, or adipose tissue—they have powerful benefits, including anti-inflammatory properties and wound-healing abilities. When combined with energy-based procedures and Topical application of Exosomes after laser

May be Faster Recovery: Reduced healing time after procedures.

May help with reducing PIH & Erythe

Maybe some Enhanced Results

How to combine Energy Based Treatments with Exosomes

Conclusion

There are currently limited extensive studies on Exosomes in aesthetic medicine. This page offers a basic understanding of how topical exosomes might be helpful in aesthetic medicine.

History of exosomes

What are exosomes(EVS & Exosomes)

Source(Human, Animal, Plant)

Content or Cargo & Heterogenecity

Endosomal pathway & Multivesicular body

Factors influencing biogenesis or cell stress

Where do you find exosomes(Cells & Fluids)

The hallmark of exosomes( Surface markers)

MOA, especially with Wound healing & Scar remodeling, cutaneous regeneration, antiaging

Diagnostic & Therapeutic benefits of exosomes

Are all exosomes the same?

Why MSC-derived Exosomes?

Concept of Cell-Free Therapy

Controversy on Exosome  source, isolation, storage, transportation and  application

At Dr. Shanthala’s office, we aim to stay at the forefront of innovative treatments while ensuring the utmost care & safety for our patients.

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Laser & Aesthetic Expert MD Boston, ShanthalaMD

Dr. Shanthala Shivananjappa

Dr. Shanthala is a board-certified, Harvard trained anesthesiologist, assistant professor at Yale University, and staff at Massachusetts General Hospital prior to opening her cosmetic medicine clinic. Her extensive experience working with plastic surgical patients in the operating room for more than 25 years, paired with years of training in non-surgical cosmetic procedures, has enabled Dr. Shanthala to have a unique perspective on Anti-aging treatments.

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