What Are Exosomes?
Exosomes are tiny vesicles, also known as extracellular vesicles, popular as acellular, secreted by almost all human, animal and plant cells. Think of them as a powerhouse of regenerative messengers of your body—they carry important information from one cell to another. These messages can be in the form of proteins, peptides, messenger RNA, micro RNA, nucleotides, enzymes, and more. While PRP is autologous, exosomes are commercially available and ready to use. For instance, if there’s inflammation in your body, a cell might release exosomes with a message saying, “Stop the inflammation.” Similarly, exosomes might send a message to speed up the healing process if there’s a wound. This ability to communicate and regulate bodily functions makes exosomes a powerful tool in aesthetic medicine.
Exosomes in Aesthetic Medicine
In this section, we’re focusing only on the topical application & regenerative benefits of exosomes in aesthetic medicine. Exosome science, as therapeutic and diagnostic research, has exploded in the last 15 years. While exosomes have a wide range of applications in fields like neurology, cardiovascular surgery, and oncology, the scope of this page is limited to their role in non-surgical aesthetic procedures.
Types of Exosomes Beneficial for My Patients
Exosomes, as we mentioned, are messengers released by cells. When these exosomes come from stem cells—such as those from bone marrow, placenta, umbilical cord, or adipose tissue—they carry powerful benefits, including anti-inflammatory properties and wound healing abilities.
In my practice, I use topical application of exosomes derived from adipose tissue, platelet-derived, and placental sources. When combined with energy-based procedures and applied topically, I’ve observed several benefits for my patients, including:
•Faster Recovery: Reduced healing time after procedures.
•Less Complications: Fewer issues such as hyperpigmentation and edema.
•Enhanced Results: Better overall outcomes from the aesthetic treatments.
Read our publication here.
Our Practice and Use of Topical Application of Exosomes
At Dr. Shanthala’s office, we prioritize safety and transparency. We only use topical exosomes that are produced and approved in the United States, ensuring the highest standards for our patients. We use them as topical for acne scars, post-laser, and microneedling procedures. While research on exosomes is ongoing, the results we’ve seen in our practice highlight their potential to improve recovery times and outcomes in non-surgical aesthetic procedures.
Conclusion
Large studies on Exosomes in aesthetic medicine is currently limited. This page offers a basic understanding of how topical exosomes are used in aesthetic medicine.
History of exosomes
What are exosomes(EVS & Exosomes)
Source(Human, Animal, Plant)
Content or Cargo & Heterogenecity
Endosomal pathway & Multivesicular body
Factors influencing biogenesis or cell stress
Where do you find exosomes(Cells & Fluids)
Hallmark of exosomes( Surface markers)
MOA especially with Wound healing & Scar remodeling, cutaneous regeneration, antiaging
Diagnostic & Therapeutic benefits of exosomes
Are all exosomes are same?
Why MSC derived Exosomes?
Concept of Cell Free Therapy
Controversy on Exosome source, isolation, storage, transportation and application
At Dr. Shanthala’s office, our goal is to stay at the forefront of innovative treatments while ensuring the utmost care for our patients. If you have any questions or are interested in learning more about how exosomes can enhance your aesthetic treatments, feel free to contact us.
